SCHEMBL30765997

SCHEMBL30765997

Cc1ccc(Nc2cccc(Cl)c2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.59
NPSR1 Q6W5P4 1/20 0.53
PGR P06401 1/20 0.51
FADS1 O60427 2/20 0.51
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
APP P05067 1/20 0.47
MAPT P10636 3/20 0.46
ALDH1A1 P00352 2/20 0.46
AR P10275 1/20 0.46
GAA P10253 2/20 0.46
TP53 P04637 1/20 0.46
G6PD P11413 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
ABCB1 P08183 1/20 0.45
ABCC1 P33527 1/20 0.45
ABCG2 Q9UNQ0 1/20 0.45
P2RX3 P56373 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7913356 1.00 HPGD (0.59) HPGDNPSR1PGRFADS1MEN1
SCHEMBL2150085 0.92 HPGD (0.58) HPGDNPSR1PGRFADS1MEN1
SCHEMBL4544831 0.88 APP (0.62) HPGDFADS1MEN1KMT2AAPP
SCHEMBL1685626 0.85 HPGD (0.73) HPGDNPSR1MEN1KMT2AAPP
SCHEMBL1686631 0.85 FADS1 (0.59) FADS1MEN1KMT2AMAPTALDH1A1
SCHEMBL12154879 0.84 APP (0.58) HPGDMEN1KMT2AAPPMAPT
SCHEMBL3951892 0.83 MEN1 (0.68) HPGDNPSR1FADS1MEN1KMT2A
SCHEMBL30342506 0.83 MEN1 (0.68) HPGDNPSR1FADS1MEN1KMT2A
SCHEMBL6351957 0.82 PKM (0.55) FADS1MEN1KMT2AMAPTALDH1A1
SCHEMBL9480224 0.82 HPGD (0.49) HPGDNPSR1PGRFADS1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113999120-B Preparation method of halogenated aniline compound 郑州原理生物科技有限公司 2024-02-27 CN disclosed