Sugi Predict

Sugi Predict / Compounds / SCHEMBL30766013

SCHEMBL30766013

SCHEMBL30766013

C[C@@H](Nc1cnc(-c2ccc(O[C@@H]3CO[C@H]4[C@@H]3OC[C@H]4OCc3ccccc3)cc2)n(CC(=O)OC(C)(C)C)c1=O)c1ccc2oc3ccccc3c2c1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ KLK7 P49862 10/20 0.40
▸ KLK5 Q9Y337 8/20 0.40
▸ ELANE P08246 8/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30765793 0.92 CASP1 (0.34) ELANE
SCHEMBL30765842 0.91 GAA (0.38) KLK7KLK5ELANE
SCHEMBL30765991 0.84 ELANE (0.42) ELANE
SCHEMBL30765695 0.84 CASP1 (0.38) ELANE
SCHEMBL30765763 0.84 ELANE (0.38) ELANE
SCHEMBL30765508 0.82 GAA (0.39) ELANE
SCHEMBL30766052 0.81 KLK7 (0.42) KLK7KLK5ELANE
SCHEMBL30765856 0.80 KLK7 (0.40) KLK7KLK5ELANE
SCHEMBL30765960 0.79 ELANE (0.36) ELANE
SCHEMBL30765798 0.79 ELANE (0.35) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4568666-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS Alexion Pharmaceuticals, Inc. (US) 2025-06-18 — — EP disclosed
WO-2024035686-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2024-02-15 — — WO disclosed