Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AVPR1B | P47901 | 6/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31558435 | 0.74 | ELANE (0.45) | CASP1LMNAELANECMA1 | |
| SCHEMBL31558531 | 0.70 | ELANE (0.38) | CASP1ELANECMA1 | |
| SCHEMBL31558468 | 0.70 | ELANE (0.36) | ELANECMA1 | |
| SCHEMBL31558524 | 0.70 | ELANE (0.35) | CASP1LMNAELANEALDH1A1CMA1 | |
| SCHEMBL31558409 | 0.68 | POLB (0.36) | LMNAELANEALDH1A1MAPT | |
| SCHEMBL31558458 | 0.67 | LIPG (0.36) | GAALMNAELANEALDH1A1 | |
| SCHEMBL31558557 | 0.65 | POLB (0.37) | GAALMNAMCHR1ALDH1A1MAPT | |
| SCHEMBL31558463 | 0.63 | MMP12 (0.35) | GAALMNAALDH1A1 | |
| SCHEMBL31558470 | 0.63 | LMNA (0.37) | GAALMNAELANEALDH1A1 | |
| SCHEMBL31558449 | 0.62 | CYP1A2 (0.38) | GAAL3MBTL1AVPR1BLMNAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |