Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30767584 | 1.00 | MDM2 (0.33) | MDM2FPR2HDAC6AGTR1AGTR2 | |
| SCHEMBL30767484 | 1.00 | MDM2 (0.33) | MDM2FPR2HDAC6AGTR1AGTR2 | |
| SCHEMBL30767535 | 0.94 | FPR2 (0.32) | FPR2RORC | |
| SCHEMBL30767447 | 0.94 | FPR2 (0.32) | FPR2RORC | |
| SCHEMBL30767430 | 0.94 | FPR2 (0.32) | FPR2RORC | |
| SCHEMBL30767620 | 0.93 | F10 (0.32) | FPR2 | |
| SCHEMBL30767676 | 0.93 | F10 (0.32) | FPR2 | |
| SCHEMBL30767408 | 0.93 | F10 (0.32) | FPR2 | |
| SCHEMBL30767553 | 0.91 | — | — | |
| SCHEMBL30767493 | 0.91 | KDM4D (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568960-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033458-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | disclosed |