Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.39 |
| ▸ | MELK | Q14680 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30767750 | 0.84 | MAP4K4 (0.47) | GRM4FFAR4MELKPTGDR2NPC1 | |
| SCHEMBL27377079 | 0.83 | GRM4 (0.46) | GRM4MELKGRM2DRD2DRD4 | |
| SCHEMBL30767760 | 0.81 | PTGDR2 (0.45) | GRM4RIPK2FFAR4MELKPTGDR2 | |
| SCHEMBL1194641 | 0.79 | DRD2 (0.51) | FFAR4PTGDR2NPC1RAB9ADRD2 | |
| SCHEMBL182167 | 0.79 | ADH5 (0.47) | GRM4MELKGRM2NPC1RAB9A | |
| SCHEMBL11486254 | 0.76 | QPCT (0.49) | FFAR4PTGDR2NPC1RAB9ADRD2 | |
| SCHEMBL27377074 | 0.73 | GRM4 (0.46) | GRM4MELKDYRK1B | |
| SCHEMBL27376813 | 0.73 | GRM4 (0.46) | GRM4MELKGRM2DRD2DRD4 | |
| SCHEMBL17125408 | 0.72 | CA12 (0.46) | RIPK2MELKPTGDR2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL30751306 | 0.72 | GRM4 (0.45) | GRM4MELKGRM2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024014851-A1 | NOVEL PURINE DERIVATIVE COMPOUNDS AS HIF-1 PROTEIN INHIBITOR | 주식회사 넥스트젠바이오사이언스 | 2024-01-18 | — | — | WO | disclosed |