Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 5/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 8/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27035007 | 1.00 | CYP11B2 (0.41) | CYP11B2ACACBSCD5PIK3R1PIK3CA | |
| SCHEMBL27034849 | 0.86 | CYP11B2 (0.41) | CYP11B2ACACBSCD5PIK3R1PIK3CA | |
| SCHEMBL30768105 | 0.86 | CYP11B2 (0.41) | CYP11B2ACACBSCD5PIK3R1PIK3CA | |
| SCHEMBL27059290 | 0.81 | PDE9A (0.36) | — | |
| SCHEMBL27034828 | 0.79 | CCNE1 (0.39) | CYP11B2CCNA2CDK2 | |
| SCHEMBL30327698 | 0.74 | CYP11B2 (0.46) | CYP11B2ACACBSCD5PIK3R1PIK3CA | |
| SCHEMBL20203405 | 0.72 | MEN1 (0.40) | — | |
| SCHEMBL30328978 | 0.70 | CYP11B2 (0.48) | CYP11B2ACACBPIK3R1PIK3CACCNA2 | |
| SCHEMBL30328647 | 0.69 | CYP11B2 (0.50) | CYP11B2ACACBSCD5PIK3R1PIK3CA | |
| SCHEMBL30328998 | 0.69 | CYP11B2 (0.46) | CYP11B2ACACBSCD5HDAC2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558502-A1 | AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE | Iambic Therapeutics, Inc. (US) | 2025-05-28 | — | — | EP | disclosed |
| CN-120051470-A | Azaquinazoline compounds and methods of use | 依安彼克医疗有限公司 | 2025-05-27 | — | — | CN | disclosed |
| WO-2024020419-A1 | AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE | IAMBIC THERAPEUTICS, INC. (US) | 2024-01-25 | — | — | WO | disclosed |