Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 5/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27035115 | 1.00 | LMNA (0.44) | LMNAALDH1A1RECQLDPP7PNMT | |
| SCHEMBL22898424 | 0.84 | LMNA (0.51) | LMNAALDH1A1DPP7PNMTADRA2A | |
| SCHEMBL17797682 | 0.80 | MEN1 (0.44) | LMNAALDH1A1DPP7PNMTADRA2A | |
| SCHEMBL31591040 | 0.78 | PDK2 (0.43) | ALDH1A1MMP8L3MBTL1MMP3 | |
| SCHEMBL27034994 | 0.78 | PDK2 (0.43) | ALDH1A1MMP8L3MBTL1MMP3 | |
| SCHEMBL3187597 | 0.77 | ESR1 (0.61) | LMNAALDH1A1PNMTADRA2AAKR1C3 | |
| SCHEMBL4135021 | 0.77 | AKR1C3 (0.58) | LMNAALDH1A1RECQLPNMTADRA2A | |
| SCHEMBL30561523 | 0.77 | AKR1C3 (0.58) | LMNAALDH1A1RECQLPNMTADRA2A | |
| SCHEMBL21526447 | 0.76 | DPP7 (0.41) | LMNAALDH1A1DPP7PNMTADRA2A | |
| SCHEMBL31591048 | 0.76 | PNMT (0.48) | PNMTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558502-A1 | AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE | Iambic Therapeutics, Inc. (US) | 2025-05-28 | — | — | EP | disclosed |
| CN-120051470-A | Azaquinazoline compounds and methods of use | 依安彼克医疗有限公司 | 2025-05-27 | — | — | CN | disclosed |
| WO-2024020419-A1 | AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE | IAMBIC THERAPEUTICS, INC. (US) | 2024-01-25 | — | — | WO | disclosed |