Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5372057 | 0.84 | MEN1 (0.47) | MEN1POLBMAPK1KMT2AADRA2A | |
| SCHEMBL30856993 | 0.76 | MEN1 (0.43) | MEN1POLBMAPK1KMT2AADRA2A | |
| Pivalate SCHEMBL30711319 | 0.72 | KMT2A (0.38) | MEN1POLBMAPK1KMT2AMAOA | |
| SCHEMBL18299637 | 0.68 | PDE2A (0.32) | MEN1POLBMAPK1KMT2AKDM4E | |
| SCHEMBL30644862 | 0.68 | BRD4 (0.34) | MEN1POLBMAPK1KMT2AKDM4E | |
| SCHEMBL7291754 | 0.68 | CCR8 (0.46) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL18239642 | 0.68 | BRD4 (0.34) | MEN1POLBMAPK1KMT2AKDM4E | |
| SCHEMBL4798726 | 0.67 | CYP1A2 (0.40) | KMT2AKDM4EBRD4TAF1BRPF1 | |
| SCHEMBL1748919 | 0.67 | MEN1 (0.48) | MEN1POLBMAPK1KMT2AKDR | |
| SCHEMBL4484912 | 0.66 | AHR (0.47) | BRD4TAF1BRPF1CREBBPCECR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500499-A | Substituted indole compounds and methods of use thereof | 奇努克治疗公司 | 2024-02-02 | — | — | CN | disclosed |