Baxdrostat

Baxdrostat

SCHEMBL30768271

CCC(=O)NC1CCCc2c(-c3ccc4c(c3)CCC(=O)N4C)cncc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 20/20 1.00
CYP11B1 P15538 17/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Baxdrostat SCHEMBL14799508 1.00 CYP11B2 (1.00) CYP11B2CYP11B1
Baxdrostat SCHEMBL30768266 1.00 CYP11B2 (1.00) CYP11B2CYP11B1
Baxdrostat SCHEMBL14799507 1.00 CYP11B2 (1.00) CYP11B2CYP11B1
Baxdrostat SCHEMBL14799753 1.00 CYP11B2 (1.00) CYP11B2CYP11B1
SCHEMBL31180372 0.96 CYP11B2 (0.93) CYP11B2CYP11B1
SCHEMBL14799875 0.95 CYP11B2 (1.00) CYP11B2CYP11B1
SCHEMBL14799650 0.95 CYP11B2 (1.00) CYP11B2CYP11B1
SCHEMBL14799849 0.95 CYP11B2 (1.00) CYP11B2CYP11B1
SCHEMBL31180329 0.94 CYP11B2 (0.88) CYP11B2CYP11B1
SCHEMBL31180342 0.93 CYP11B2 (0.87) CYP11B2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277698-A1 METHODS OF USING ALDOSTERONE SYNTHASE INHIBITORS CINCOR PHARMA, INC. 2024-08-22 US disclosed
CN-117545482-A Methods of using aldosterone synthase inhibitors 新科药业公司 2024-02-09 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240277698-A1 METHODS OF USING ALDOSTERONE SYNTHASE INHIBITORS HSD11B1, CYP17A1, CYP21A2 CYP11B2 7/4885CYP11B1 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.