Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 4/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SI | P14410 | 2/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26696346 | 1.00 | GUSB (0.59) | GUSBDYRK1AMGAMGAASI | |
| SCHEMBL30768353 | 0.83 | GUSB (0.40) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL26696375 | 0.83 | GUSB (0.40) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL26696394 | 0.83 | GUSB (0.52) | GUSBDYRK1AMGAMGAASI | |
| SCHEMBL30039498 | 0.78 | GUSB (0.89) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL28579017 | 0.78 | GUSB (0.89) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL30768386 | 0.78 | GUSB (0.47) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL26696392 | 0.78 | GUSB (0.47) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL26696391 | 0.78 | GUSB (0.40) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL24145199 | 0.75 | GUSB (0.75) | GUSBMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382926-A1 | COMPOUNDS AND USES THEREOF | THE UNIVERSITY OF THE WEST INDIES (TT) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382926-A1 | COMPOUNDS AND USES THEREOF | CFTR, CCL11, CEL | GUSB 111/4885DYRK1A 4777/4885MGAM 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.