Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24749512 | 1.00 | TDP1 (0.51) | TDP1RAB9AMEN1KMT2AXDH | |
| SCHEMBL29938615 | 0.95 | TDP1 (0.47) | TDP1RAB9AMEN1KMT2AXDH | |
| SCHEMBL30768319 | 0.86 | SOS1 (0.42) | TDP1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5192099 | 0.84 | ABCB1 (0.45) | TDP1SIRT6PDGFRBFGFR1PDGFRA | |
| SCHEMBL21072635 | 0.84 | XDH (0.58) | TDP1RAB9AXDHALDH1A1HPGD | |
| SCHEMBL24750235 | 0.83 | CTSD (0.50) | TDP1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL31009332 | 0.82 | HPGD (0.50) | TDP1MEN1KMT2AXDHALDH1A1 | |
| SCHEMBL1571262 | 0.82 | AKR1C3 (0.54) | RAB9AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7688039 | 0.80 | MEN1 (0.45) | TDP1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL31009338 | 0.79 | MAPT (0.52) | TDP1MEN1KMT2AXDHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500786-A | TEAD inhibitors | 奥赖恩公司 | 2024-02-02 | — | — | CN | disclosed |