Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 8/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.34 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 3/20 | 0.32 |
| ▸ | BTK | Q06187 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1900607 | 0.90 | BCL2L1 (0.42) | LPLLIPGP2RX7MAPK1JAK2 | |
| SCHEMBL12667047 | 0.90 | P2RX7 (0.39) | LPLLIPGP2RX7MAPK1JAK2 | |
| SCHEMBL29432478 | 0.84 | CYP2A6 (0.40) | LPLLIPGP2RX7MAPK1JAK2 | |
| SCHEMBL31394843 | 0.82 | MAPK1 (0.41) | LPLLIPGP2RX7MAPK1BACE1 | |
| SCHEMBL31394538 | 0.82 | MAPK1 (0.41) | LPLLIPGP2RX7MAPK1CA12 | |
| SCHEMBL31394907 | 0.82 | MAPK1 (0.41) | LPLLIPGP2RX7MAPK1CA12 | |
| SCHEMBL31394111 | 0.82 | MAPK1 (0.41) | LPLLIPGP2RX7MAPK1BACE1 | |
| SCHEMBL16760796 | 0.81 | CD44 (0.47) | P2RX7 | |
| SCHEMBL31707905 | 0.80 | ALDH1A1 (0.37) | LPLLIPGP2RX7MAPK1JAK2 | |
| SCHEMBL508291 | 0.80 | ALDH1A1 (0.37) | LPLLIPGP2RX7MAPK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543871-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024006781-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |