SCHEMBL30769064

SCHEMBL30769064

Cc1cc(I)cc(F)c1Br

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17157357 1.00 AKR1B1 (0.31) AKR1B1
SCHEMBL855169 0.82 KDM1A (0.39) AKR1B1
SCHEMBL15262205 0.82 TTR (0.36)
SCHEMBL13550059 0.75 NQO2 (0.32) AKR1B1
SCHEMBL29863733 0.75 RAPGEF4 (0.40)
SCHEMBL24699771 0.75 TTR (0.32)
SCHEMBL29664557 0.75 NQO2 (0.32) AKR1B1
SCHEMBL1043169 0.75 RAPGEF4 (0.40)
SCHEMBL11992628 0.75 RAPGEF4 (0.34)
SCHEMBL17733622 0.75 TTR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543871-A1 ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF Relay Therapeutics, Inc. (US) 2025-04-30 EP disclosed
CN-119110795-A Compounds and compositions for treating conditions associated with LPA receptor activity 罗特斯生物公司 2024-12-10 CN disclosed
WO-2024006781-A1 ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF RELAY THERAPEUTICS, INC. (US) 2024-01-04 WO disclosed