Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | LGMN | Q99538 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SUV39H2 | Q9H5I1 | 4/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30768476 | 0.84 | MAPT (0.42) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL29683460 | 0.84 | DPP4 (0.36) | MAPTLMNAMEN1KMT2ALGMN | |
| SCHEMBL20211889 | 0.84 | DPP4 (0.36) | MAPTLMNAMEN1KMT2ALGMN | |
| SCHEMBL24847849 | 0.81 | DPP4 (0.38) | TSHRMAPTLMNAMEN1KMT2A | |
| SCHEMBL20231014 | 0.80 | IGF1R (0.42) | ADRB1MAPTLMNAMEN1KMT2A | |
| SCHEMBL29927711 | 0.78 | ALDH1A1 (0.47) | POLBMAPTLMNAMEN1KMT2A | |
| SCHEMBL25134014 | 0.78 | ALDH1A1 (0.47) | POLBMAPTLMNAMEN1KMT2A | |
| SCHEMBL30643679 | 0.78 | NPY5R (0.41) | ADRB1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL26641199 | 0.78 | NPY5R (0.41) | ADRB1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL24319603 | 0.76 | SIRT6 (0.41) | MAPTLMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543871-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024169871-A1 | BTK INHIBITOR AND USE THEREOF | 江苏威凯尔医药科技有限公司 | 2024-08-22 | — | — | WO | disclosed |
| CN-118515673-A | BTK inhibitor and application thereof | 江苏威凯尔医药科技有限公司 | 2024-08-20 | — | — | CN | disclosed |
| WO-2024006781-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |