Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.45 |
| ▸ | NAAA | Q02083 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10945592 | 0.85 | NPSR1 (0.55) | HCAR2NPSR1SMN1; SMN2GAA | |
| SCHEMBL10945607 | 0.85 | NPSR1 (0.55) | HCAR2NPSR1SMN1; SMN2GAA | |
| SCHEMBL5612673 | 0.81 | ATM (0.46) | HCAR2NAAAATMTSHRNPSR1 | |
| SCHEMBL5612679 | 0.81 | ATM (0.46) | HCAR2NAAAATMTSHRNPSR1 | |
| SCHEMBL5611993 | 0.79 | NPSR1 (0.52) | HCAR2NPSR1SMN1; SMN2GAA | |
| SCHEMBL5611998 | 0.79 | NPSR1 (0.52) | HCAR2NPSR1SMN1; SMN2GAA | |
| SCHEMBL5612661 | 0.78 | NAAA (0.40) | NAAATSHRNPSR1FAAHSMN1; SMN2 | |
| SCHEMBL5612684 | 0.77 | NPSR1 (0.50) | HCAR2ATMNPSR1HPGDHTT | |
| SCHEMBL20530266 | 0.77 | NPSR1 (0.50) | HCAR2ATMNPSR1HPGDHTT | |
| SCHEMBL5612678 | 0.77 | NPSR1 (0.50) | HCAR2ATMNPSR1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756590-A | Method for preparing alpha, beta unsaturated succinate compound | 中国科学院大连化学物理研究所 | 2024-03-26 | — | — | CN | disclosed |