Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5612673 | 1.00 | ATM (0.46) | ATMTSHRHPGDHCAR2NAAA | |
| SCHEMBL27619484 | 0.88 | HCAR2 (0.41) | ATMTSHRHPGDHCAR2NAAA | |
| SCHEMBL28166491 | 0.82 | TSHR (0.44) | ATMTSHRHCAR2NAAANPSR1 | |
| SCHEMBL9364396 | 0.82 | TSHR (0.42) | TSHRHCAR2NAAANPSR1EPHX2 | |
| SCHEMBL9364395 | 0.82 | TSHR (0.42) | TSHRHCAR2NAAANPSR1EPHX2 | |
| SCHEMBL5612678 | 0.81 | NPSR1 (0.50) | ATMHPGDHCAR2MAPTNPSR1 | |
| SCHEMBL20530266 | 0.81 | NPSR1 (0.50) | ATMHPGDHCAR2MAPTNPSR1 | |
| SCHEMBL5612684 | 0.81 | NPSR1 (0.50) | ATMHPGDHCAR2MAPTNPSR1 | |
| SCHEMBL30769638 | 0.81 | HCAR2 (0.45) | ATMTSHRHPGDHCAR2NAAA | |
| SCHEMBL5611998 | 0.80 | NPSR1 (0.52) | HCAR2RAB9AMAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425317-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE SRL (IT) | 2007-12-19 | — | — | EP | disclosed |
| US-7015170-B2 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2006-03-21 | — | — | US | disclosed |
| EP-1425317-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.p.A. (IT) | 2004-06-09 | — | — | EP | disclosed |
| US-20040014595-A1 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-01-22 | — | — | US | disclosed |
| WO-2003022894-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-03-20 | — | — | WO | disclosed |