Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 19/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.51 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132105 | 0.87 | PIK3CB (0.55) | PIK3CBPIK3CAPIK3CDPIK3CGPIK3R1 | |
| SCHEMBL16268102 | 0.79 | PIK3CB (0.75) | PIK3CBPIK3CAPIK3CDPIK3CGPIK3R1 | |
| SCHEMBL2217551 | 0.69 | SMN1; SMN2 (0.65) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2219072 | 0.68 | SMN1; SMN2 (0.64) | SMN1; SMN2 | |
| SCHEMBL29358326 | 0.67 | PIK3CB (1.00) | PIK3CBPIK3CAPIK3CDPIK3CGPIK3R1 | |
| SCHEMBL902952 | 0.67 | PIK3CB (1.00) | PIK3CBPIK3CAPIK3CDPIK3CGPIK3R1 | |
| SCHEMBL16340412 | 0.65 | HTR1A (0.41) | SMN1; SMN2 | |
| SCHEMBL31303956 | 0.65 | ADORA3 (0.41) | PIK3CBPIK3CAPIK3CDPIK3CGPIK3R1 | |
| SCHEMBL15887180 | 0.64 | PIM1 (0.44) | PIK3CBPIK3CAPIK3CDSMN1; SMN2 | |
| SCHEMBL2219070 | 0.63 | SMN1; SMN2 (0.65) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023230577-A1 | METHODS OF TREATING CANCER WITH AN MTOR INHIBITOR | Revolution Medicines, Inc. (US) | 2023-11-30 | — | — | WO | disclosed |