Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | PTPN22 | Q9Y2R2 | 4/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12586119 | 1.00 | ALDH1A1 (0.55) | ALDH1A1CA12CA1CA2TSHR | |
| SCHEMBL1505143 | 0.86 | AKR1C2 (0.52) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL5158868 | 0.86 | AKR1C2 (0.52) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL2325383 | 0.84 | ALDH1A1 (0.64) | ALDH1A1TSHRPDK1PDK2PDK3 | |
| SCHEMBL24436789 | 0.83 | CA12 (0.64) | ALDH1A1CA12CA1CA2TSHR | |
| SCHEMBL518632 | 0.82 | PIM1 (0.53) | AURKATPX2AKR1C2AKR1C1IGF2BP2 | |
| SCHEMBL8493525 | 0.81 | AKR1C2 (0.58) | TSHRAURKATPX2AKR1C2AKR1C1 | |
| SCHEMBL22497443 | 0.81 | ALDH1A1 (0.57) | ALDH1A1AURKATPX2AKR1C2AKR1C1 | |
| SCHEMBL11820792 | 0.81 | AKR1C2 (0.48) | ALDH1A1AURKATPX2AKR1C2AKR1C1 | |
| SCHEMBL966871 | 0.81 | RXRB (0.50) | ALDH1A1AURKATPX2AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558500-A1 | IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | Sanofi (FR) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024017977-A1 | IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2024-01-25 | — | — | WO | disclosed |