Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20681369 | 1.00 | NLRP3 (0.38) | NLRP3ACHECYP1A2CYP2C9TSHR | |
| SCHEMBL20692313 | 0.79 | NLRP3 (0.40) | NLRP3UGT2B17 | |
| SCHEMBL22282197 | 0.79 | NLRP3 (0.38) | NLRP3UGT2B17 | |
| SCHEMBL30041743 | 0.79 | BCHE (0.32) | BCHE | |
| SCHEMBL23674551 | 0.79 | BCHE (0.32) | BCHE | |
| SCHEMBL23674508 | 0.79 | BCHE (0.32) | BCHE | |
| SCHEMBL20692050 | 0.79 | BCHE (0.32) | BCHE | |
| SCHEMBL22002675 | 0.79 | NLRP3 (0.40) | NLRP3UGT2B17 | |
| SCHEMBL22012824 | 0.79 | NLRP3 (0.40) | NLRP3UGT2B17 | |
| SCHEMBL23674470 | 0.79 | LMNA (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3880659-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2024-01-03 | — | — | EP | disclosed |