SCHEMBL30770801

SCHEMBL30770801

COc1ccc(-c2cc3ccccc3[nH]2)cc1OC

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.67
KDM4E B2RXH2 6/20 0.67
NPC1 O15118 6/20 0.67
MAPT P10636 5/20 0.67
CASP3 P42574 2/20 0.67
SENP8 Q96LD8 2/20 0.67
SENP7 Q9BQF6 2/20 0.67
SENP6 Q9GZR1 2/20 0.67
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
ALDH1A1 P00352 3/20 0.62
HPGD P15428 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
NPSR1 Q6W5P4 1/20 0.62
CYP1A2 P05177 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
CHEK1 O14757 1/20 0.51
FGFR1 P11362 1/20 0.51
CDK4 P11802 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10796083 1.00 RAB9A (0.67) RAB9AKDM4ENPC1MAPTCASP3
SCHEMBL11653277 0.89 RAB9A (0.57) RAB9AKDM4ENPC1MAPTCASP3
SCHEMBL11654006 0.89 MAPT (0.57) RAB9AKDM4ENPC1MAPTCASP3
SCHEMBL11659391 0.88 KDM4E (0.63) RAB9AKDM4ENPC1MAPTCASP3
SCHEMBL11654467 0.86 RAB9A (0.55) RAB9AKDM4ENPC1MAPTCASP3
SCHEMBL11531160 0.86 RAB9A (0.55) RAB9AKDM4ENPC1MAPTCASP3
SCHEMBL17422798 0.86 RAB9A (0.61) RAB9AKDM4ENPC1MAPTCASP3
SCHEMBL6503284 0.86 RAB9A (0.61) RAB9AKDM4ENPC1MAPTCASP3
SCHEMBL11117167 0.86 RAB9A (0.61) RAB9AKDM4ENPC1MAPTCASP3
SCHEMBL11411064 0.86 CDK4 (0.67) RAB9AKDM4ENPC1MAPTCASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250391519-A1 CHEMICAL SYNTHESIS PLATFORM UNIV GLASGOW COURT (GB) 2025-12-25 US disclosed
EP-4548355-A1 CHEMICAL SYNTHESIS PLATFORM The University Court Of The University Of Glasgow (GB) 2025-05-07 EP disclosed
WO-2024003151-A1 CHEMICAL SYNTHESIS PLATFORM THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) 2024-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250391519-A1 CHEMICAL SYNTHESIS PLATFORM SET, CBS, COASY RAB9A 3727/4885KDM4E 1077/4885NPC1 849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.