Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 3/20 | 0.36 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295277 | 1.00 | QPCT (0.36) | QPCTMRGPRX1ABL1P2RY14PIK3CA | |
| SCHEMBL21303614 | 0.84 | ABL1 (0.38) | QPCTMRGPRX1ABL1P2RY14MAPT | |
| SCHEMBL21295263 | 0.84 | PIK3CA (0.38) | QPCTABL1P2RY14PIK3CAMAPT | |
| SCHEMBL22440199 | 0.82 | MAPT (0.40) | QPCTABL1P2RY14PIK3CAMAPT | |
| SCHEMBL22440207 | 0.78 | MAPT (0.53) | QPCTABL1PIK3CAMAPTKDM4E | |
| SCHEMBL21295258 | 0.75 | LTA4H (0.35) | QPCTABL1P2RY14 | |
| SCHEMBL22440183 | 0.74 | QPCT (0.47) | QPCTP2RY14MAPTKDM4EMEN1 | |
| SCHEMBL22440192 | 0.73 | DHFR (0.51) | QPCTPIK3CADHFR | |
| SCHEMBL22440185 | 0.71 | MAPT (0.54) | QPCTMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL22440191 | 0.69 | QPCT (0.49) | QPCTABL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757883-B | Novel inhibitors of bacterial glutaminyl cyclase for the treatment of periodontal disease and related diseases | 弗劳恩霍夫应用研究促进协会 | 2024-02-13 | — | — | CN | disclosed |