Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20600200 | 0.76 | CSNK2A1 (0.48) | CSNK2A2CSNK2BCSNK2A1HTTCYP1A2 | |
| SCHEMBL30824209 | 0.76 | CSNK2A1 (0.48) | CSNK2A2CSNK2BCSNK2A1HTTCYP1A2 | |
| SCHEMBL10086124 | 0.74 | HTT (0.54) | CSNK2A2CSNK2BCSNK2A1HTTSMN1; SMN2 | |
| SCHEMBL22050219 | 0.70 | CSNK2A2 (0.38) | HCAR2CSNK2A2CSNK2BCSNK2A1KDM5A | |
| SCHEMBL20111331 | 0.68 | HCAR2 (0.46) | POLBHCAR2KDM4CHTTCYP1A2 | |
| SCHEMBL659061 | 0.67 | HCAR2 (0.42) | POLBHCAR2KDM4CCYP1A2HSD17B10 | |
| SCHEMBL15334246 | 0.66 | AKR1C3 (0.50) | POLBHCAR2KDM4CKDM4EALDH1A1 | |
| SCHEMBL21749937 | 0.66 | HCAR2 (0.41) | POLBHCAR2KDM4CHSD17B10KDM4E | |
| SCHEMBL20621866 | 0.65 | HSD17B10 (0.42) | CSNK2A2CSNK2BCSNK2A1HTTCYP1A2 | |
| SCHEMBL20621867 | 0.65 | CCNC (0.36) | CSNK2A2CSNK2BCSNK2A1HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346616-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) | 2025-11-13 | — | — | US | disclosed |
| EP-4532484-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2025-04-09 | — | — | EP | disclosed |
| CN-119173509-A | ROCK inhibitors and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-12-20 | — | — | CN | disclosed |
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346616-A1 | ROCK INHIBITORS AND USES THEREOF | ROCK1, ROCK2, RHOA | POLB 4141/4885HCAR2 3363/4885CSNK2A2 915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.