Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 7/20 | 0.65 |
| ▸ | KCNMA1 | Q12791 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | AURKA | O14965 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.62 |
| ▸ | JAK2 | O60674 | 1/20 | 0.62 |
| ▸ | GMNN | O75496 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | LYN | P07948 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | KIT | P10721 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26979798 | 1.00 | P2RX1 (0.65) | P2RX1KCNMA1MEN1AURKANPC1 | |
| SCHEMBL26095536 | 0.84 | KMT2A (0.77) | P2RX1KCNMA1MEN1AURKANPC1 | |
| SCHEMBL8057066 | 0.82 | MEN1 (0.78) | P2RX1KCNMA1MEN1AURKANPC1 | |
| SCHEMBL30100393 | 0.82 | MEN1 (0.78) | P2RX1KCNMA1MEN1AURKANPC1 | |
| SCHEMBL23303584 | 0.81 | P2RX1 (0.80) | P2RX1KCNMA1MEN1AURKANPC1 | |
| SCHEMBL30771718 | 0.80 | KCNMA1 (0.75) | P2RX1KCNMA1MEN1AURKANPC1 | |
| SCHEMBL18341405 | 0.80 | KCNMA1 (0.75) | P2RX1KCNMA1MEN1AURKANPC1 | |
| SCHEMBL18341255 | 0.80 | P2RX1 (0.74) | P2RX1KCNMA1MEN1AURKANPC1 | |
| SCHEMBL31238369 | 0.79 | TAS1R3 (0.86) | P2RX1KCNMA1MEN1AURKANPC1 | |
| SCHEMBL8054842 | 0.79 | P2RX1 (0.81) | P2RX1KCNMA1MEN1AURKANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002332-A1 | Small Molecule Inhibitors of SARS-CoV-2 Infections | THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION | 2024-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240002332-A1 | Small Molecule Inhibitors of SARS-CoV-2 Infections | ACE2, ACE, TMPRSS2 | P2RX1 2669/4885KCNMA1 3777/4885MEN1 4741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.