SCHEMBL30771995

SCHEMBL30771995

CCOC(=O)COC1CCC2(CC1)CCN(C)CC2

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 5/20 0.42
ITGA2B P08514 5/20 0.42
OPRM1 P35372 7/20 0.38
SLC22A1 O15245 1/20 0.38
SLC6A4 P31645 1/20 0.38
ADRA1A P35348 1/20 0.38
OPRD1 P41143 1/20 0.38
OPRK1 P41145 1/20 0.38
KCNH2 Q12809 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8912151 0.85 ITGB3 (0.46) ITGB3ITGA2BKMT2ATSHR
SCHEMBL12774203 0.77 CHRM1 (0.45) ITGB3ITGA2BKMT2A
SCHEMBL10742501 0.77 GAA (0.41) ITGB3ITGA2BKMT2A
SCHEMBL3248382 0.74 KMT2A (0.51) ITGB3ITGA2BKMT2ATSHR
SCHEMBL3248583 0.74 KMT2A (0.47) ITGB3ITGA2BKMT2ATSHR
SCHEMBL12881695 0.74 ALDH1A1 (0.39) ITGB3ITGA2BKMT2A
SCHEMBL14587568 0.74 SMN1; SMN2 (0.52) KMT2A
SCHEMBL3252087 0.73 KMT2A (0.50) ITGB3ITGA2BKMT2A
SCHEMBL20234347 0.73 KMT2A (0.42) ITGB3ITGA2BKMT2ATSHR
SCHEMBL3256401 0.73 KMT2A (0.50) ITGB3ITGA2BKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024001839-A1 HETEROAROMATIC RING COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2024-01-04 WO disclosed