Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 6/20 | 0.90 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.90 |
| ▸ | ALPL | P05186 | 2/20 | 0.90 |
| ▸ | ALPI | P09923 | 2/20 | 0.90 |
| ▸ | ALPG | P10696 | 1/20 | 0.90 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.89 |
| ▸ | GAA | P10253 | 6/20 | 0.89 |
| ▸ | POLB | P06746 | 5/20 | 0.89 |
| ▸ | MAPT | P10636 | 4/20 | 0.89 |
| ▸ | APEX1 | P27695 | 2/20 | 0.89 |
| ▸ | RECQL | P46063 | 1/20 | 0.79 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.79 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.79 |
| ▸ | MAOA | P21397 | 4/20 | 0.79 |
| ▸ | XDH | P47989 | 4/20 | 0.79 |
| ▸ | SLCO2B1 | O94956 | 3/20 | 0.79 |
| ▸ | CA12 | O43570 | 2/20 | 0.79 |
| ▸ | CA2 | P00918 | 2/20 | 0.79 |
| ▸ | CA4 | P22748 | 2/20 | 0.79 |
| ▸ | CA7 | P43166 | 2/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20801984 | 1.00 | P4HB (0.90) | P4HBL3MBTL1ALPLALPIALPG | |
| SCHEMBL5086742 | 1.00 | P4HB (0.90) | P4HBL3MBTL1ALPLALPIALPG | |
| SCHEMBL31720515 | 1.00 | P4HB (0.90) | P4HBL3MBTL1ALPLALPIALPG | |
| SCHEMBL20802110 | 0.96 | KDM4E (0.83) | P4HBL3MBTL1ALPLALPIALPG | |
| SCHEMBL20801873 | 0.96 | KDM4E (0.83) | P4HBL3MBTL1ALPLALPIALPG | |
| SCHEMBL20801883 | 0.96 | KDM4E (0.83) | P4HBL3MBTL1ALPLALPIALPG | |
| SCHEMBL20801877 | 0.95 | KDM4E (0.98) | P4HBL3MBTL1ALPLALPIALPG | |
| SCHEMBL20801872 | 0.95 | KDM4E (0.98) | P4HBL3MBTL1ALPLALPIALPG | |
| SCHEMBL20801876 | 0.95 | KDM4E (0.98) | P4HBL3MBTL1ALPLALPIALPG | |
| SCHEMBL29724190 | 0.95 | KDM4E (0.98) | P4HBL3MBTL1ALPLALPIALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3655015-B1 | COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING RADIATION-INDUCED BYSTANDER EFFECTS CAUSED BY RADIATION OR RADIOTHERAPY | UNIV COLORADO REGENTS (US) | 2024-02-21 | — | — | EP | disclosed |