SCHEMBL20801872

SCHEMBL20801872

O=c1c(O[C@@H]2OC(CO)[C@@H](O)C(O)C2O[C@@H]2OC(CO)[C@@H](O)C(O)C2O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12

nearest known ligand 0.98

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 0.98
▸ GAA P10253 5/20 0.98
▸ POLB P06746 4/20 0.98
▸ MAPT P10636 3/20 0.98
▸ APEX1 P27695 2/20 0.98
▸ RECQL P46063 1/20 0.87
▸ P4HB P07237 6/20 0.87
▸ EPHX2 P34913 5/20 0.87
▸ AKR1B1 P15121 4/20 0.87
▸ ALPL P05186 2/20 0.87
▸ ALPI P09923 2/20 0.87
▸ CA12 O43570 2/20 0.87
▸ CA2 P00918 2/20 0.87
▸ CA4 P22748 2/20 0.87
▸ CA7 P43166 2/20 0.87
▸ ADRA2C P18825 1/20 0.87
▸ NOX4 Q9NPH5 1/20 0.87
▸ KDM1A O60341 1/20 0.87
▸ SLCO2B1 O94956 1/20 0.87
▸ HMGB1 P09429 1/20 0.87

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29724190 1.00 KDM4E (0.98) KDM4EGAAPOLBMAPTAPEX1
SCHEMBL20801876 1.00 KDM4E (0.98) KDM4EGAAPOLBMAPTAPEX1
SCHEMBL20801877 1.00 KDM4E (0.98) KDM4EGAAPOLBMAPTAPEX1
SCHEMBL27617329 1.00 KDM4E (0.98) KDM4EGAAPOLBMAPTAPEX1
SCHEMBL23070285 0.99 KDM4E (1.00) KDM4EGAAPOLBMAPTAPEX1
SCHEMBL29897592 0.99 KDM4E (1.00) KDM4EGAAPOLBMAPTAPEX1
SCHEMBL30637437 0.96 KDM4E (0.91) KDM4EGAAPOLBMAPTAPEX1
SCHEMBL20801984 0.95 P4HB (0.90) KDM4EGAAPOLBMAPTAPEX1
SCHEMBL30772282 0.95 P4HB (0.90) KDM4EGAAPOLBMAPTAPEX1
SCHEMBL31720515 0.95 P4HB (0.90) KDM4EGAAPOLBMAPTAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10765128-B2 Composition for prevention or treatment of metabolic syndrome or for antioxidation containing black bean leaf extracts and flavonol glysosides isolated therefrom as active ingredients KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2020-09-08 — — US disclosed
US-20190075823-A1 COMPOSITION FOR PREVENTION OR TREATMENT OF METABOLIC SYNDROME OR FOR ANTIOXIDATION CONTAINING BLACK BEAN LEAF EXTRACTS AND FLAVONOL GLYSOSIDES ISOLATED THEREFROM AS ACTIVE INGREDIENTS KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2019-03-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10765128-B2 Composition for prevention or treatment of metabolic syndrome or for antioxidation containing black bean leaf extracts and flavonol glysosides isolated therefrom as active ingredients GPX1, GSTP1, GSS KDM4E 4058/4885GAA 92/4885POLB 2591/4885
US-20190075823-A1 COMPOSITION FOR PREVENTION OR TREATMENT OF METABOLIC SYNDROME OR FOR ANTIOXIDATION CONTAINING BLACK BEAN LEAF EXTRACTS AND FLAVONOL GLYSOSIDES ISOLATED THEREFROM AS ACTIVE INGREDIENTS GPX1, GSTP1, PON1 KDM4E 4169/4885GAA 144/4885POLB 3461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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