Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 3/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2803755 | 1.00 | PDE5A (0.41) | PDE5AACP1KDM1AGBA1GGPS1 | |
| SCHEMBL3811994 | 0.87 | PDE5A (0.46) | PDE5AACP1KDM1AGBA1GGPS1 | |
| SCHEMBL3706548 | 0.87 | PDE5A (0.47) | PDE5AKDM1AGBA1ADORA3ADORA2A | |
| SCHEMBL3706663 | 0.86 | CCNE2 (0.48) | PDE5AKDM1AGBA1MEN1MAPT | |
| SCHEMBL3708230 | 0.84 | PDE5A (0.61) | PDE5AKDM1AGBA1MEN1MAPT | |
| SCHEMBL13088248 | 0.84 | PDE5A (0.47) | PDE5AACP1KDM1AGBA1GGPS1 | |
| SCHEMBL3782101 | 0.80 | GBA1 (0.47) | PDE5AACP1GBA1MEN1KMT2A | |
| SCHEMBL3782097 | 0.80 | GBA1 (0.47) | PDE5AACP1GBA1MEN1KMT2A | |
| SCHEMBL2803161 | 0.78 | PDE5A (0.47) | PDE5AACP1KDM1AGBA1GGPS1 | |
| SCHEMBL3809901 | 0.75 | PDE5A (0.49) | PDE5AKDM1AGBA1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119932083-A | Double-base pichia pastoris base editor and application | 中国人民解放军军事科学院军事医学研究院 | 2025-05-06 | — | — | CN | disclosed |
| CN-118146151-A | 4-Trifluoromethyl substituted quinoline and quinazoline compound and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2024-06-07 | — | — | CN | disclosed |
| EP-2718755-B1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL INC (US) | 2024-05-29 | — | — | EP | disclosed |
| WO-2024069121-A1 | NETWORK-AGNOSTIC SYSTEM TO FACILITATE PEER-TO-PEER TRANSFERS | IPCO 2012 LIMITED (GB) | 2024-04-04 | — | — | WO | disclosed |
| US-20240104527-A1 | NETWORK-AGNOSTIC SYSTEM TO FACILITATE PEER-TO-PEER TRANSFERS | VOCALINK INTERNATIONAL LIMITED (GB) | 2024-03-28 | — | — | US | disclosed |