Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATIC | P31939 | 3/20 | 0.47 |
| ▸ | FBP1 | P09467 | 2/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.46 |
| ▸ | DNPH1 | O43598 | 3/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12878250 | 0.82 | P2RY2 (0.48) | ATICFBP1P2RY2TAS1R3TAS1R1 | |
| SCHEMBL22684942 | 0.79 | ATIC (0.65) | ATICFBP1P2RY2TAS1R3TAS1R1 | |
| SCHEMBL29136140 | 0.76 | ATIC (0.62) | ATICFBP1P2RY2TAS1R3TAS1R1 | |
| SCHEMBL19876125 | 0.76 | ATIC (0.62) | ATICFBP1P2RY2TAS1R3TAS1R1 | |
| SCHEMBL188235 | 0.76 | ATIC (0.62) | ATICFBP1P2RY2TAS1R3TAS1R1 | |
| SCHEMBL2936680 | 0.74 | ATIC (0.54) | ATICFBP1P2RY2TAS1R3TAS1R1 | |
| Cyclohexane SCHEMBL9842969 | 0.73 | ATIC (0.59) | ATICFBP1P2RY2TAS1R3TAS1R1 | |
| SCHEMBL9240378 | 0.70 | FBP1 (0.55) | ATICFBP1P2RY2TAS1R3TAS1R1 | |
| Perflexane SCHEMBL7515566 | 0.69 | ATIC (0.54) | ATICFBP1P2RY2TAS1R3TAS1R1 | |
| SCHEMBL8346987 | 0.69 | FBP1 (0.53) | ATICFBP1P2RY2TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117440829-A | Pharmaceutical combination for the treatment of cancer | T3制药股份公司 | 2024-01-23 | — | — | CN | disclosed |