SCHEMBL30773467

SCHEMBL30773467

N=C(N)NCCC[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 13/20 0.55
▸ NPY1R P25929 8/20 0.55
▸ NPY2R P49146 6/20 0.55
▸ NPY5R Q15761 6/20 0.55
▸ TFPI P10646 1/20 0.49
▸ KISS1R Q969F8 4/20 0.48
▸ ERAP2 Q6P179 1/20 0.48
▸ LNPEP Q9UIQ6 1/20 0.48
▸ VIPR1 P32241 1/20 0.47
▸ VIPR2 P41587 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30342387 0.94 TFPI (0.57) NPY4RNPY1RNPY2RNPY5RTFPI
SCHEMBL30274541 0.92 NPY4R (0.63) NPY4RNPY1RNPY2RNPY5RERAP2
SCHEMBL30123583 0.91 NPY4R (0.59) NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL30153268 0.91 NPY4R (0.65) NPY4RNPY1RNPY2RNPY5R
SCHEMBL31188458 0.91 NPY4R (0.65) NPY4RNPY1RNPY2RNPY5R
SCHEMBL30939704 0.90 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5RTFPI
SCHEMBL31232432 0.90 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5RTFPI
SCHEMBL5965061 0.90 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5RTFPI
SCHEMBL5965085 0.90 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5RTFPI
SCHEMBL30939697 0.90 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5RTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024040122-A2 SENSE-AND-RESPONSE OF PROTEINS, PEPTIDES, AND SMALL MOLECULES USING LIGAND-INDUCED DIMERIZATION ACTIVATING RNA EDITING (LIDAR) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-02-22 — — WO disclosed
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