SCHEMBL30773914

SCHEMBL30773914

N=C(N)NCCC[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 4/20 0.57
▸ NPY4R P50391 6/20 0.57
▸ NPY1R P25929 5/20 0.57
▸ NPY2R P49146 5/20 0.57
▸ PRKACB P22694 1/20 0.55
▸ UTS2R Q9UKP6 1/20 0.55
▸ NPBWR1 P48145 1/20 0.53
▸ NPY5R Q15761 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30118086 1.00 GHSR (0.57) GHSRNPY4RNPY1RNPY2RPRKACB
SCHEMBL29641180 0.99 GHSR (0.58) GHSRNPY4RNPY1RNPY2RPRKACB
SCHEMBL29641082 0.97 GHSR (0.61) GHSRNPY4RNPY1RNPY2RPRKACB
SCHEMBL29641066 0.97 GHSR (0.61) GHSRNPY4RNPY1RNPY2RPRKACB
SCHEMBL30169478 0.95 GHSR (0.65) GHSRNPY4RNPY1RNPY2RUTS2R
SCHEMBL29641169 0.95 GHSR (0.65) GHSRNPY4RNPY1RNPY2RUTS2R
SCHEMBL29641033 0.95 GHSR (0.65) GHSRNPY4RNPY1RNPY2RUTS2R
SCHEMBL29641067 0.95 GHSR (0.65) GHSRNPY4RNPY1RNPY2RUTS2R
SCHEMBL31193767 0.95 NPY4R (0.60) GHSRNPY4RNPY1RNPY2RNPY5R
SCHEMBL29576199 0.94 GHSR (0.54) GHSRNPY4RNPY1RNPY2RPRKACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240059735-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MITOCHONDRIAL MYOPATHIES STEALTH BIOTHERAPEUTICS INC. (US) 2024-02-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240059735-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MITOCHONDRIAL MYOPATHIES MTPN, CKMT1A; CKMT1B, TFAM GHSR 4526/4885NPY4R 3458/4885NPY1R 3326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback