SCHEMBL30773965

SCHEMBL30773965

N#Cc1ccc(-c2cncc3c2OCCN3C(=O)Cc2ccc(Cl)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 3/20 0.40
▸ NAAA Q02083 2/20 0.40
▸ EIF4A3 P38919 1/20 0.39
▸ CNR1 P21554 1/20 0.39
▸ SLC22A12 Q96S37 3/20 0.38
▸ DRD2 P14416 1/20 0.37
▸ DRD4 P21917 1/20 0.37
▸ RIPK1 Q13546 1/20 0.37
▸ S1PR1 P21453 2/20 0.36
▸ S1PR3 Q99500 2/20 0.36
▸ PANK3 Q9H999 1/20 0.35
▸ CYP11B2 P19099 2/20 0.35
▸ FNTA P49354 1/20 0.35
▸ FNTB P49356 1/20 0.35
▸ CYP11B1 P15538 1/20 0.35
▸ CYP2C9 P11712 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774868 0.91 NAAA (0.43) NAAAEIF4A3CNR1SLC22A12DRD2
SCHEMBL30774026 0.91 NAAA (0.40) FAAHNAAASLC22A12PANK3CYP11B2
SCHEMBL30773967 0.91 NAAA (0.40) FAAHNAAASLC22A12DRD2CYP11B2
SCHEMBL30774028 0.89 NAAA (0.40) FAAHNAAASLC22A12RIPK1CYP11B2
SCHEMBL30773952 0.88 SMN1; SMN2 (0.42) FAAHNAAADRD2CYP2C9
SCHEMBL30774594 0.88 STAT3 (0.42) FAAHNAAASLC22A12RIPK1PANK3
SCHEMBL30774875 0.86 SLC22A12 (0.39) SLC22A12CYP11B2CYP11B1
SCHEMBL30774866 0.85 POLB (0.47) EIF4A3SLC22A12FNTAFNTB
SCHEMBL30774857 0.85 SLC22A12 (0.40) SLC22A12CYP11B2CYP11B1
SCHEMBL30774747 0.84 SLC22A12 (0.39) SLC22A12RIPK1CYP11B2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP disclosed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 FAAH 1677/4885NAAA 1168/4885EIF4A3 1499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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