SCHEMBL30774868

SCHEMBL30774868

N#Cc1ccc(-c2cncc3c2OCCN3C(=O)CCc2ccc(Cl)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ NAAA Q02083 2/20 0.43
▸ SLC22A12 Q96S37 3/20 0.42
▸ EIF4A3 P38919 1/20 0.38
▸ DRD2 P14416 1/20 0.36
▸ DRD4 P21917 1/20 0.36
▸ CNR1 P21554 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ ME2 P23368 1/20 0.35
▸ ME1 P48163 1/20 0.35
▸ ME3 Q16798 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ EGLN2 Q96KS0 1/20 0.35
▸ EP300 Q09472 1/20 0.34
▸ CYP11B2 P19099 1/20 0.34
▸ MAP4K4 O95819 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774003 0.91 NAAA (0.44) NAAASLC22A12DRD2ME2ME1
SCHEMBL30773965 0.91 FAAH (0.40) NAAASLC22A12EIF4A3DRD2DRD4
SCHEMBL30773992 0.90 NAAA (0.47) NAAASLC22A12EGLN2
SCHEMBL30773961 0.89 MAPT (0.44) SLC22A12DRD2ALDH1A1ME2ME1
SCHEMBL30774365 0.89 STAT3 (0.41) NAAASLC22A12
SCHEMBL30774875 0.85 SLC22A12 (0.39) SLC22A12CYP11B2
SCHEMBL30773960 0.84 NAAA (0.46) NAAASLC22A12DRD2CYP11B2
SCHEMBL30774866 0.84 POLB (0.47) SLC22A12EIF4A3
SCHEMBL30774857 0.83 SLC22A12 (0.40) SLC22A12CYP11B2
SCHEMBL30774747 0.83 SLC22A12 (0.39) SLC22A12CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP disclosed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 NAAA 1168/4885SLC22A12 3869/4885EIF4A3 1499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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