Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 8/20 | 0.60 |
| ▸ | TUBB | P07437 | 8/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.60 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.60 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.60 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.60 |
| ▸ | TUBB2B | Q9BVA1 | 8/20 | 0.60 |
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.60 |
| ▸ | PDE2A | O00408 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609689 | 0.78 | TUBB4A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL21328451 | 0.76 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL21333199 | 0.76 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL21328455 | 0.74 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL21328453 | 0.74 | TUBB3 (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL21340917 | 0.74 | TUBB4A (0.73) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL21328446 | 0.73 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13828287 | 0.72 | PDE2A (0.57) | PDE2AKMT2AMEN1 | |
| SCHEMBL30774335 | 0.72 | TUBB4A (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29540122 | 0.72 | TUBB4A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624063-A | Heterocyclic compound and application thereof | 中国科学院上海药物研究所 | 2024-03-01 | — | — | CN | disclosed |