SCHEMBL30774570

SCHEMBL30774570

Cc1ccccc1CC(=O)N1CCc2c(-c3ccc(C#N)cc3)cncc21

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ EIF2AK3 Q9NZJ5 1/20 0.44
▸ SCN2A Q99250 1/20 0.43
▸ SCN10A Q9Y5Y9 1/20 0.43
▸ CYP11B2 P19099 16/20 0.43
▸ CYP11B1 P15538 13/20 0.43
▸ UCHL1 P09936 1/20 0.42
▸ USP30 Q70CQ3 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774340 0.90 USP30 (0.42) CYP11B2CYP11B1UCHL1USP30
SCHEMBL30774477 0.89 EIF2AK3 (0.43) EIF2AK3CYP11B2CYP11B1UCHL1USP30
SCHEMBL30774583 0.85 USP30 (0.42) CYP11B2CYP11B1UCHL1USP30
SCHEMBL30774574 0.84 CYP11B2 (0.44) EIF2AK3CYP11B2CYP11B1UCHL1USP30
SCHEMBL30773955 0.84 SCN2A (0.42) EIF2AK3SCN2ASCN10ACYP11B2CYP11B1
SCHEMBL30774523 0.83 CYP11B2 (0.45) CYP11B2CYP11B1UCHL1USP30
SCHEMBL30774383 0.83 RIPK1 (0.46) EIF2AK3CYP11B2CYP11B1UCHL1USP30
SCHEMBL30774510 0.82 CYP11B2 (0.44) CYP11B2CYP11B1UCHL1USP30
SCHEMBL30774465 0.81 CYP11B2 (0.46) CYP11B2CYP11B1UCHL1USP30
SCHEMBL30774460 0.80 CYP11B2 (0.44) CYP11B2CYP11B1UCHL1USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US claimed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP disclosed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 EIF2AK3 1947/4885SCN2A 2468/4885SCN10A 1558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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