Styrene

Styrene

SCHEMBL3077494

C=C(C(=O)OCCN)C(C)C.C=Cc1ccccc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.38
TSHR P16473 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
IDO1 P14902 1/20 0.37
CASP1 P29466 1/20 0.36
MAPT P10636 4/20 0.35
LMNA P02545 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
HPGD P15428 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TAS1R3 Q7RTX0 1/20 0.34
TAS1R1 Q7RTX1 1/20 0.34
PTGS2 P35354 1/20 0.34
ADRB2 P07550 1/20 0.34
HTR1A P08908 1/20 0.34
NPSR1 Q6W5P4 2/20 0.33
XBP1 P17861 1/20 0.33
ATM Q13315 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL7646017 0.89 TSHR (0.42) ALDH1A1TSHRMEN1KMT2ACASP1
SCHEMBL5411652 0.85 POLB (0.38) ALDH1A1MEN1KMT2AIDO1LMNA
Acrylic Acid SCHEMBL8037578 0.81 TSHR (0.34) TSHRLMNAHPGD
Styrene SCHEMBL3091250 0.81 ALDH1A1 (0.40) ALDH1A1TSHRMEN1KMT2AIDO1
SCHEMBL41031 0.81 TSHR (0.36) TSHRTHRB
Acetic Acid SCHEMBL8433810 0.79 TSHR (0.37) TSHRTHRB
Styrene SCHEMBL9517582 0.79 CYP2C19 (0.38) ALDH1A1TSHRMEN1KMT2AIDO1
Styrene SCHEMBL19582868 0.79 ALDH1A1 (0.36) ALDH1A1TSHRMEN1KMT2AIDO1
Hydrochloric Acid SCHEMBL2533776 0.79 TSHR (0.35) TSHRIDO1LMNATHRB
Ammonia Solution, Strong SCHEMBL3663515 0.79 TSHR (0.35) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58118655-A None JP disclosed
EP-1686426-B1 Toner and method of manufacturing the toner RICOH CO LTD (JP) 2012-11-21 EP disclosed
US-7858280-B2 Toner and image forming method using the same RICOH COMPANY, LTD. (JP) 2010-12-28 US disclosed
US-7790343-B2 Process, toner, process cartridge and apparatus for developing a toner image RICOH COMPANY, LTD. (JP) 2010-09-07 US disclosed
US-20070218386-A1 PROCESS, TONER, PROCESS CARTRIDGE AND APPARATUS FOR DEVELOPING A TONER IMAGE RICOH COMPANY, LTD. (JP) 2007-09-20 US disclosed
US-20060177756-A1 Toner and image forming method using the same RICOH COMPANY, LTD. (JP) 2006-08-10 US disclosed
EP-1686426-A2 Toner and image forming method using the same Ricoh Company, Ltd. (JP) 2006-08-02 EP disclosed
JP-S58118655-A ELECTROPHOTOGRAPHIC TONER CANON INC 1983-07-14 JP disclosed