Acrylic Acid

Acrylic Acid

SCHEMBL8037578

C=C(C(=O)OCCN)C(C)C.C=CC(=O)O

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.34
LMNA P02545 2/20 0.33
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CTH P32929 1/20 0.31
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylamide SCHEMBL9647386 0.90 TSHR (0.37) TSHRHPGD
SCHEMBL41031 0.89 TSHR (0.36) TSHR
Acetic Acid SCHEMBL8433810 0.88 TSHR (0.37) TSHRCTH
Hydrochloric Acid SCHEMBL2533776 0.88 TSHR (0.35) TSHRLMNA
Ammonia Solution, Strong SCHEMBL3663515 0.88 TSHR (0.35) TSHR
Acrylamide SCHEMBL4446874 0.87 TSHR (0.34) TSHR
Chloromethane SCHEMBL543091 0.86 TSHR (0.34) TSHR
Sulfuric Acid SCHEMBL5068577 0.83 TSHR (0.32) TSHR
SCHEMBL13372705 0.82 TSHR (0.33) TSHR
Styrene SCHEMBL3077494 0.81 ALDH1A1 (0.38) TSHRLMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6066279-A GELCASTING OF A MIXTURE OF HYDROXYMETHYLACRYLAMIDE, AN AQUEOUS SOLVENT, AND AN INORGANIC POWDER LOCKHEED MARTIN ENERGY RESEARCH CORP. (US) 2000-05-23 US disclosed
US-5013452-A Adding an amine demulsifier PETROLITE CORPORATION (US) 1991-05-07 US disclosed
EP-0029317-B1 PRODUCTION OF MALEIC ANHYDRIDE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-03-19 EP disclosed
EP-0003431-B1 PRODUCTION OF CARBOXYLIC ACID ANHYDRIDES AND CATALYSTS THEREFOR IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-04-11 EP disclosed
US-4352755-A Production of maleic anhydride IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-10-05 US disclosed
EP-0029317-A1 Production of maleic anhydride IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-05-27 EP disclosed
US-4222945-A OXIDATION OF HYDROCARBON WITH VANADIUM-PHOSPHORUS MIXED OXIDE CATALYST IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-09-16 US disclosed
EP-0003431-A1 Production of carboxylic acid anhydrides and catalysts therefor IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-08-08 EP disclosed