Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3071644 | 0.84 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP3A4TSHRPARP1LMNA | |
| SCHEMBL28263886 | 0.75 | SMN1; SMN2 (0.60) | SMN1; SMN2CYP3A4TSHRLMNAGAA | |
| SCHEMBL9768399 | 0.73 | PTPRC (0.39) | SMN1; SMN2TSHRLMNAALDH1A1MAPT | |
| SCHEMBL27479602 | 0.73 | ACHE (0.39) | TSHRLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL47585 | 0.72 | GABRA1 (0.48) | SMN1; SMN2CYP3A4GAAMAPTDHODH | |
| SCHEMBL27972883 | 0.68 | DHODH (0.35) | SMN1; SMN2CYP3A4TSHRPARP1GAA | |
| SCHEMBL10950133 | 0.67 | TAAR1 (0.48) | LMNAALDH1A1MAPTHTTKMT2A | |
| SCHEMBL8545783 | 0.67 | KMT2A (0.36) | SMN1; SMN2CYP3A4PARP1ALDH1A1MEN1 | |
| SCHEMBL11222215 | 0.66 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP3A4TSHRPARP1LMNA | |
| SCHEMBL27731314 | 0.65 | TDP1 (0.40) | SMN1; SMN2GAAALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592738-B1 | RESIN COMPOSITIONS | CIBA HOLDING INC (CH) | 2020-07-29 | — | — | EP | disclosed |
| US-7790793-B2 | Amide nucleating agent compositions | CIBA SPECIALTY CHEM. CORP. (US) | 2010-09-07 | — | — | US | disclosed |
| US-20070149663-A1 | Resin compositions | CIBA SPECIALTY CHEMICALS CORP. | 2007-06-28 | — | — | US | disclosed |
| EP-1592738-A2 | RESIN COMPOSITIONS | Ciba SC Holding AG (CH) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004072168-A2 | RESIN COMPOSITIONS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-08-26 | — | — | WO | disclosed |