Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.44 |
| ▸ | RORC | P51449 | 4/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29135477 | 1.00 | TSHR (0.45) | TSHRALOX15ATMUSP30RORC | |
| SCHEMBL27167101 | 0.91 | TSHR (0.47) | TSHRALOX15ATMUSP30RORC | |
| SCHEMBL30056366 | 0.91 | TSHR (0.47) | TSHRALOX15ATMUSP30RORC | |
| SCHEMBL28029029 | 0.86 | TSHR (0.52) | TSHRALOX15ATMUSP30RORC | |
| SCHEMBL31694033 | 0.86 | TSHR (0.52) | TSHRALOX15ATMUSP30RORC | |
| SCHEMBL19331220 | 0.85 | TSHR (0.48) | TSHRALOX15ATMUSP30RORC | |
| SCHEMBL38652021 | 0.83 | USP30 (0.49) | TSHRALOX15ATMUSP30RORC | |
| SCHEMBL19690249 | 0.81 | TSHR (0.46) | TSHRALOX15ATMUSP30RORC | |
| SCHEMBL30056364 | 0.81 | TACR1 (0.46) | TSHRALOX15ATMUSP30RORC | |
| SCHEMBL27167111 | 0.81 | TACR1 (0.46) | TSHRALOX15ATMUSP30RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355522-A | PKC-theta modulators | 爱智药人工智能有限公司 | 2024-01-05 | — | — | CN | disclosed |