SCHEMBL30776643

SCHEMBL30776643

NC(=O)c1ccccc1NC(=O)CN1CCOCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
KDM4E B2RXH2 2/20 1.00
SMN1; SMN2 Q16637 2/20 0.66
MAPT P10636 1/20 0.66
MEN1 O00255 1/20 0.64
KMT2A Q03164 1/20 0.64
LMNA P02545 3/20 0.63
TDP1 Q9NUW8 1/20 0.57
POLB P06746 1/20 0.56
HTT P42858 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10914817 0.83 ALDH1A1 (0.71) ALDH1A1KDM4EMEN1KMT2ALMNA
Hydrochloric Acid SCHEMBL10911639 0.82 ALDH1A1 (0.70) ALDH1A1KDM4EMEN1KMT2ALMNA
SCHEMBL6174299 0.82 ALDH1A1 (0.69) ALDH1A1KDM4ESMN1; SMN2MAPTMEN1
SCHEMBL30776656 0.81 KDM4E (0.68) ALDH1A1KDM4ESMN1; SMN2MAPTMEN1
SCHEMBL30776659 0.81 ALDH1A1 (0.67) ALDH1A1KDM4EMAPTMEN1KMT2A
Hydrochloric Acid SCHEMBL10914024 0.80 MEN1 (0.74) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL11465420 0.80 ALDH1A1 (0.66) ALDH1A1KDM4EMEN1KMT2APOLB
SCHEMBL1643927 0.78 ALDH1A1 (0.76) ALDH1A1KDM4ESMN1; SMN2MAPTMEN1
SCHEMBL24489123 0.78 MEN1 (0.64) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL29694124 0.78 MEN1 (0.64) ALDH1A1KDM4EMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117586233-A Preparation and application of N- [ (1H-indol-4-yl) alkyl ] benzamide compound 沈阳药科大学 2024-02-23 CN disclosed