Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | BCL3 | P20749 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4524250 | 0.92 | KDM4E (0.63) | ALDH1A1KDM4EBCL3POLBKMT2A | |
| SCHEMBL11465415 | 0.86 | DRD3 (0.51) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL11454492 | 0.85 | POLB (0.49) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL11448262 | 0.84 | HTR1A (0.58) | POLBMEN1KMT2A | |
| SCHEMBL11446935 | 0.84 | KDM4E (0.46) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11605251 | 0.84 | KDM4E (0.46) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL11465072 | 0.83 | KDM4E (0.50) | ALDH1A1KDM4EPOLBKMT2APARP1 | |
| SCHEMBL2463879 | 0.83 | KDM4E (0.58) | ALDH1A1KDM4EPOLBPARP1HPGD | |
| Hydrochloric Acid SCHEMBL11500448 | 0.83 | HTR1A (0.57) | POLBMEN1KMT2A | |
| SCHEMBL11605256 | 0.82 | KMT2A (0.54) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4205173-A | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof | PENNWALT CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |
| US-4085107-A | ANALGESICS | PENNWALT CORPORATION (US) | 1978-04-18 | — | — | US | disclosed |
| US-4060526-A | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof | PENNWALT CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |