Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF1 | P18846 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | BRAF | P15056 | 7/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
| ▸ | ARAF | P10398 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | PNLIP | P16233 | 1/20 | 0.42 |
| ▸ | GCK | P35557 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30777864 | 1.00 | ATF1 (0.47) | ATF1NFKB1BRAFHDAC1HDAC3 | |
| SCHEMBL17530353 | 1.00 | ATF1 (0.47) | ATF1NFKB1BRAFHDAC1HDAC3 | |
| SCHEMBL17542402 | 0.92 | TDP1 (0.44) | ATF1NFKB1BRAFHDAC1HDAC3 | |
| SCHEMBL21524954 | 0.90 | BRAF (0.40) | ATF1NFKB1BRAFHDAC1HDAC3 | |
| SCHEMBL30777869 | 0.87 | KMT2A (0.47) | ATF1NFKB1PNLIPP2RX1 | |
| SCHEMBL17530358 | 0.87 | KMT2A (0.47) | ATF1NFKB1PNLIPP2RX1 | |
| SCHEMBL17530347 | 0.84 | ATF1 (0.43) | ATF1NFKB1BRAFGRM4PNLIP | |
| SCHEMBL12303377 | 0.79 | CFTR (0.46) | BRAFHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL17530356 | 0.77 | BRAF (0.59) | BRAFHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL17350355 | 0.76 | BRAF (0.64) | BRAFHDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3792251-B1 | NOVEL SULFONYLAMINOBENZAMIDE COMPOUNDS AS ANTHELMINTICS | ELANCO TIERGESUNDHEIT AG (CH) | 2024-02-14 | — | — | EP | disclosed |