Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 11/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.64 |
| ▸ | FADS1 | O60427 | 1/20 | 0.51 |
| ▸ | PNLIP | P16233 | 8/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.51 |
| ▸ | RAF1 | P04049 | 2/20 | 0.50 |
| ▸ | ARAF | P10398 | 2/20 | 0.50 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530356 | 0.91 | BRAF (0.59) | BRAFHDAC1FADS1PNLIPHDAC3 | |
| SCHEMBL17350309 | 0.83 | TDP1 (0.52) | BRAFHDAC1PNLIPSTK39 | |
| SCHEMBL17350275 | 0.81 | FADS1 (0.52) | BRAFHDAC1FADS1HDAC8HDAC6 | |
| SCHEMBL17351022 | 0.79 | KDM4E (0.53) | BRAFHDAC1PNLIPSTK39 | |
| SCHEMBL23096725 | 0.78 | FADS1 (0.51) | FADS1 | |
| SCHEMBL11645838 | 0.77 | BRAF (0.70) | BRAFHDAC1PNLIPHDAC3HDAC4 | |
| SCHEMBL28322470 | 0.76 | PNLIP (0.43) | BRAFHDAC1PNLIPSTK39 | |
| SCHEMBL30777864 | 0.76 | ATF1 (0.47) | BRAFHDAC1FADS1PNLIPHDAC3 | |
| SCHEMBL30777867 | 0.76 | ATF1 (0.47) | BRAFHDAC1FADS1PNLIPHDAC3 | |
| SCHEMBL17530353 | 0.76 | ATF1 (0.47) | BRAFHDAC1FADS1PNLIPHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106470972-B | Sulfonylaminobenzamide compounds | 瑞士伊兰科动物保健有限公司 | 2019-10-18 | — | — | CN | disclosed |
| US-9714219-B2 | Sulfonylaminobenzamide compounds | NOVARTIS TIERGESUNDHEIT AG (CH) | 2017-07-25 | — | — | US | disclosed |
| EP-3157902-A1 | NEW SULFONYLAMINOBENZAMIDE COMPOUNDS | Novartis Tiergesundheit AG (CH) | 2017-04-26 | — | — | EP | disclosed |
| CN-106470972-A | Sulfonylaminobenzamide compounds | 瑞士诺华动物保健有限公司 | 2017-03-01 | — | — | CN | disclosed |
| US-20160221937-A1 | NEW SULFONYLAMINOBENZAMIDE COMPOUNDS | ELANCO TIERGESUNDHEIT AG (CH) | 2016-08-04 | — | — | US | disclosed |
| EP-2957555-A1 | METHOD FOR MODIFYING DERIVATIVES OF AMINO ACIDS AND PEPTIDES, COMPOUNDS PRODUCED, AND USE | Consejo Superior De Investigaciones Científicas (CSIC) (ES) | 2015-12-23 | — | — | EP | disclosed |
| EP-2957557-A1 | New compounds | Novartis Tiergesundheit AG (CH) | 2015-12-23 | — | — | EP | disclosed |
| WO-2015195423-A1 | NEW SULFONYLAMINOBENZAMIDE COMPOUNDS | NOVARTIS TIERGESUNDHEIT AG (CH) | 2015-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160221937-A1 | NEW SULFONYLAMINOBENZAMIDE COMPOUNDS | PKD2, PKD1, GBA1 | BRAF 1335/4885HDAC1 532/4885FADS1 4340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.