Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | PPOX | P50336 | 1/20 | 0.47 |
| ▸ | ATF1 | P18846 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | PNLIP | P16233 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530358 | 1.00 | KMT2A (0.47) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL17542402 | 0.96 | TDP1 (0.44) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL30777864 | 0.87 | ATF1 (0.47) | ATF1NFKB1P2RX1PNLIP | |
| SCHEMBL17530353 | 0.87 | ATF1 (0.47) | ATF1NFKB1P2RX1PNLIP | |
| SCHEMBL30777867 | 0.87 | ATF1 (0.47) | ATF1NFKB1P2RX1PNLIP | |
| SCHEMBL17530354 | 0.82 | TDP1 (0.59) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL12303379 | 0.81 | TDP1 (0.55) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL17530347 | 0.81 | ATF1 (0.43) | KMT2AMEN1ATF1NFKB1PPARG | |
| SCHEMBL17530350 | 0.79 | SIRT6 (0.56) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL21524954 | 0.79 | BRAF (0.40) | KMT2AMEN1ATF1NFKB1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3792251-B1 | NOVEL SULFONYLAMINOBENZAMIDE COMPOUNDS AS ANTHELMINTICS | ELANCO TIERGESUNDHEIT AG (CH) | 2024-02-14 | — | — | EP | disclosed |