Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30778502 | 0.85 | RXRA (0.33) | TRPA1TRPV4CA2CHKARXRA | |
| SCHEMBL31045864 | 0.81 | PDE10A (0.43) | PTGS1PTGS2TSHRTRPV4CA2 | |
| SCHEMBL2998384 | 0.74 | HSP90AA1 (0.38) | TRPV4CA2CHKA | |
| SCHEMBL30456789 | 0.74 | HSP90AA1 (0.38) | TRPV4CA2CHKA | |
| SCHEMBL22234714 | 0.74 | ALOX5AP (0.38) | HTR2AHTR2CHTR2BP2RX3 | |
| SCHEMBL26598644 | 0.74 | KCNQ3 (0.40) | HTR2AHTR2CHTR2BP2RX3 | |
| SCHEMBL23908261 | 0.71 | PDE2A (0.37) | CYP2C19CYP3A4CYP2D6TSHRCRHBP | |
| SCHEMBL20972087 | 0.71 | PDE2A (0.37) | CYP2C19CYP3A4CYP2D6TSHRCRHBP | |
| SCHEMBL22438785 | 0.71 | PDE2A (0.37) | CYP2C19CYP3A4CYP2D6TSHRCRHBP | |
| SCHEMBL7916902 | 0.70 | PDE10A (0.40) | PTGS1PTGS2TSHRP2RX3TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024022910-A1 | 1-[1-[2-(PYRIMIDIN-4-YL)-1,2,4-TRIAZOL-3-YL]ETHYL]-3-[2,4-DICHLORO-5-PHENYL]UREA DERIVATIVES AND SIMILAR COMPOUNDS AS PESTICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2024-02-01 | — | — | WO | disclosed |