Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | KDM4B | O94953 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30779338 | 1.00 | HPGD (0.47) | HPGDHSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL27074471 | 1.00 | HPGD (0.47) | HPGDHSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL30797370 | 0.89 | HPGD (0.47) | HPGDHSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL27085692 | 0.89 | HPGD (0.47) | HPGDHSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL27075711 | 0.86 | ALDH1A1 (0.43) | HPGDHSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL30776674 | 0.86 | ALDH1A1 (0.43) | HPGDHSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL31307434 | 0.83 | HPGD (0.40) | HPGDHSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL27182113 | 0.83 | HPGD (0.40) | HPGDHSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL8630444 | 0.82 | HSD17B10 (0.60) | HPGDHSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL3598248 | 0.81 | HPGD (0.62) | HPGDHSD17B10MEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11884669-B1 | Pyrrolo[3,2-c][1,7]naphthyridine-2-carboxylic acid compounds as CK2 inhibitors | King Faisal University (SA) | 2024-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11884669-B1 | Pyrrolo[3,2-c][1,7]naphthyridine-2-carboxylic acid compounds as CK2 inhibitors | CSNK2A1, CSNK2A2, CSNK2A3 | HPGD 2741/4885HSD17B10 3285/4885MEN1 4067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.