Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268860 | 1.00 | LMNA (0.50) | LMNATP53CYP2D6MAPTSPHK1 | |
| SCHEMBL11257374 | 1.00 | LMNA (0.50) | LMNATP53CYP2D6MAPTSPHK1 | |
| SCHEMBL8625471 | 1.00 | LMNA (0.50) | LMNATP53CYP2D6MAPTSPHK1 | |
| SCHEMBL3077994 | 1.00 | LMNA (0.50) | LMNATP53CYP2D6MAPTSPHK1 | |
| SCHEMBL2494168 | 0.98 | LMNA (0.48) | LMNATP53CYP2D6MAPTSPHK1 | |
| Ammonia Solution, Strong SCHEMBL8824139 | 0.98 | LMNA (0.48) | LMNATP53CYP2D6MAPTSPHK1 | |
| SCHEMBL5581939 | 0.98 | LMNA (0.48) | LMNATP53CYP2D6MAPTSPHK1 | |
| Ammonia Solution, Strong SCHEMBL8824188 | 0.98 | LMNA (0.48) | LMNATP53CYP2D6MAPTSPHK1 | |
| SCHEMBL2362764 | 0.98 | TP53 (0.50) | LMNATP53CYP2D6MAPTSPHK1 | |
| SCHEMBL9019493 | 0.89 | PPARA (0.46) | LMNAMAPTGMNNPOLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100233114-A1 | METHODS OF STYLING HAIR | L'ORéAL S.A. (FR) | 2010-09-16 | — | — | US | disclosed |
| US-20080124296-A1 | COMPOSITIONS CONTAINING MICROSPHERES | L'OREAL S.A. (FR) | 2008-05-29 | — | — | US | disclosed |
| US-6977238-B1 | Method for making stable aqueous foaming surfactant | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2005-12-20 | — | — | US | disclosed |
| US-6949494-B2 | Synthetic detergent formulations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2005-09-27 | — | — | US | disclosed |
| EP-1005523-B1 | SYNTHETIC DETERGENT FORMULATIONS | ICI PLC (GB) | 2004-09-22 | — | — | EP | disclosed |
| US-20030114346-A1 | Synthetic detergent formulations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2003-06-19 | — | — | US | disclosed |
| US-6475972-B1 | Synthetic detergent formulations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2002-11-05 | — | — | US | disclosed |
| EP-0818984-B1 | SURFACTANT COMPOSITIONS | ICI PLC (GB) | 2002-01-30 | — | — | EP | disclosed |
| EP-1005523-A1 | SYNTHETIC DETERGENT FORMULATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999010467-A1 | SYNTHETIC DETERGENT FORMULATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1999-03-04 | — | — | WO | disclosed |
| EP-0818984-A2 | SURFACTANT COMPOSITIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996031187-A2 | SURFACTANT COMPOSITIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1996-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100233114-A1 | METHODS OF STYLING HAIR | KRT18, SUCLG1, PIK3C3 | LMNA 775/4885TP53 1893/4885CYP2D6 4542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.