Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3077994 | 0.98 | LMNA (0.50) | TP53LMNACYP2D6SPHK1GMNN | |
| SCHEMBL11257374 | 0.98 | LMNA (0.50) | TP53LMNACYP2D6SPHK1GMNN | |
| SCHEMBL8625471 | 0.98 | LMNA (0.50) | TP53LMNACYP2D6SPHK1GMNN | |
| SCHEMBL11268860 | 0.98 | LMNA (0.50) | TP53LMNACYP2D6SPHK1GMNN | |
| SCHEMBL3077941 | 0.98 | LMNA (0.50) | TP53LMNACYP2D6SPHK1GMNN | |
| Ammonia Solution, Strong SCHEMBL8824139 | 0.96 | LMNA (0.48) | TP53LMNACYP2D6SPHK1GMNN | |
| Ammonia Solution, Strong SCHEMBL8824188 | 0.96 | LMNA (0.48) | TP53LMNACYP2D6SPHK1GMNN | |
| SCHEMBL2494168 | 0.96 | LMNA (0.48) | TP53LMNACYP2D6SPHK1GMNN | |
| SCHEMBL5581939 | 0.96 | LMNA (0.48) | TP53LMNACYP2D6SPHK1GMNN | |
| SCHEMBL7612076 | 0.89 | TP53 (0.56) | TP53LMNASMN1; SMN2MAPTFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110494120-B | Method for removing corner bolts | 花王株式会社 | 2023-07-18 | — | — | CN | claimed |
| EP-3644949-B1 | SOLID CLEANING COSMETIC COMPOSITION | OREAL (FR) | 2021-10-20 | — | — | EP | claimed |
| US-20210137800-A1 | ANHYDROUS SOLID COMPOSITION COMPRISING AN ISETHIONIC ACID DERIVATIVE, A GLUTAMIC ACID DERIVATIVE, AN AMPHOTERIC SURFACTANT AND FILLERS | L'OREAL (FR) | 2021-05-13 | — | — | US | claimed |
| EP-3644949-A1 | SOLID CLEANING COSMETIC COMPOSITION | L'Oreal (FR) | 2020-05-06 | — | — | EP | claimed |
| EP-3644948-A1 | ANHYDROUS SOLID COMPOSITION COMPRISING AN ISETHIONIC ACID DERIVATIVE, A GLUTAMIC ACID DERIVATIVE, AN AMPHOTERIC SURFACTANT AND FILLERSANHYDROUS SOLID COMPOSITION COMPRISING AN ISETHIONIC ACID DERIVATIVE, A GLUTAMIC ACID DERIVATIVE, AN AMPHOTERIC SURFACTANT AND FILLERS | L'Oréal (FR) | 2020-05-06 | — | — | EP | claimed |
| CN-110945111-A | Soap block | 巴斯夫欧洲公司 | 2020-03-31 | — | — | CN | claimed |
| CN-110831568-A | Anhydrous solid composition comprising isethionic acid derivative, glutamic acid derivative, amphoteric surfactant and filler | 莱雅公司 | 2020-02-21 | — | — | CN | claimed |
| CN-110123659-A | A kind of Anti-hair loss composition and its in the application for preparing Anti-hair loss and washing in shield product | 名臣健康用品股份有限公司 | 2019-08-16 | — | — | CN | claimed |
| WO-2019001940-A1 | ANHYDROUS SOLID COMPOSITION COMPRISING AN ISETHIONIC ACID DERIVATIVE, A GLUTAMIC ACID DERIVATIVE, AN AMPHOTERIC SURFACTANT AND FILLERSANHYDROUS SOLID COMPOSITION COMPRISING AN ISETHIONIC ACID DERIVATIVE, A GLUTAMIC ACID DERIVATIVE, AN AMPHOTERIC SURFACTANT AND FILLERS | L'OREAL (FR) | 2019-01-03 | — | — | WO | claimed |
| WO-2019002374-A1 | SOLID CLEANING COSMETIC COMPOSITION | L'OREAL (FR) | 2019-01-03 | — | — | WO | claimed |
| US-20160243014-A1 | Optically Clear Acyl-Isethionate Aqueous Concentrate for Cosmetic Use | CLARIANT INTERNATIONAL AG (CH) | 2016-08-25 | — | — | US | claimed |
| WO-2015067597-A1 | OPTICALLY CLEAR ACYL-ISETHIONATE AQUEOUS CONCENTRATE FOR COSMETIC USE | OTC GMBH (DE) | 2015-05-14 | — | — | WO | claimed |
| EP-2870957-A1 | Optically clear isethionate aqueous concentrate for cosmetic use | OTC GmbH (DE) | 2015-05-13 | — | — | EP | claimed |
| EP-2021445-B1 | PROCESS COMPOSITIONS AND PRODUCTION OF ACYL ALKYLISETHIONATE COMPOSITIONS | HUNTSMAN PETROCHEMICAL LLC (US) | 2013-10-02 | — | — | EP | claimed |
| WO-2012052536-A2 | COSMETIC COMPOSITION COMPRISING ALOE VERA AND AN ISETHIONIC ACID DERIVATIVE | L'OREAL (FR) | 2012-04-26 | — | — | WO | claimed |
| WO-2011102834-A1 | COMFORT SOAP CLEANSER | Chanel Inc. (US) | 2011-08-25 | — | — | WO | claimed |
| US-20080299065-A1 | COMPOSITION CONTAINING SULFONIC ACID AND/OR SULFURIC ACID COMPOUND | L'OREAL (FR) | 2008-12-04 | — | — | US | claimed |
| EP-1343863-B1 | SKIN CLEANSING BAR WITH HIGH LEVELS OF LIQUID EMOLLIENT | UNILEVER PLC (GB) | 2004-07-14 | — | — | EP | claimed |
| EP-0353013-B1 | WIPING ARTICLE | UNILEVER PLC (GB) | 1993-09-15 | — | — | EP | claimed |
| EP-0189332-B1 | TOILET BARS | UNILEVER PLC (GB) | 1991-09-25 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210137800-A1 | ANHYDROUS SOLID COMPOSITION COMPRISING AN ISETHIONIC ACID DERIVATIVE, A GLUTAMIC ACID DERIVATIVE, AN AMPHOTERIC SURFACTANT AND FILLERS | S100A4, KRT18, S100P | TP53 165/4885LMNA 1196/4885SMN1; SMN2 3466/4885 |
| US-20080299065-A1 | COMPOSITION CONTAINING SULFONIC ACID AND/OR SULFURIC ACID COMPOUND | STS, MPST, TST | TP53 442/4885LMNA 3323/4885SMN1; SMN2 916/4885 |
| US-20160243014-A1 | Optically Clear Acyl-Isethionate Aqueous Concentrate for Cosmetic Use | ASNS, GATD3, IDUA | TP53 1296/4885LMNA 4350/4885SMN1; SMN2 3162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.