Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | DDX3X | O00571 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3475933 | 0.95 | NPC1 (0.67) | MAPTLMNAPOLBGAANPC1 | |
| SCHEMBL30321478 | 0.93 | NPC1 (0.56) | MAPTLMNAPOLBGAANPC1 | |
| SCHEMBL8397659 | 0.93 | NPC1 (0.56) | MAPTLMNAPOLBGAANPC1 | |
| SCHEMBL19675710 | 0.87 | CTSL (0.57) | MAPTLMNAPOLBGAANPC1 | |
| SCHEMBL3821145 | 0.86 | CTSL (0.61) | MAPTLMNAPOLBGAANPC1 | |
| SCHEMBL19675959 | 0.84 | NPC1 (0.52) | MAPTLMNAPOLBGAANPC1 | |
| SCHEMBL1197657 | 0.84 | PKM (0.68) | MAPTLMNAPOLBGAANPC1 | |
| SCHEMBL15271967 | 0.83 | SMN1; SMN2 (0.53) | MAPTLMNAPOLBNPC1RAB9A | |
| SCHEMBL29757387 | 0.80 | MAPT (0.93) | MAPTLMNAPOLBGAACTSL | |
| SCHEMBL12485644 | 0.77 | CTSL (0.57) | MAPTLMNAPOLBGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030651-A1 | GPX4 INHIBITORS AND USE THEREOF | SONATA THERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |