Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP1A1 | P05023 | 1/20 | 0.49 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.49 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.49 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.49 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.49 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.49 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.49 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | VDR | P11473 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29113087 | 0.81 | KMT2A (0.51) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL31147714 | 0.68 | MAPT (0.42) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL28305771 | 0.67 | ALDH1A1 (0.58) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL3401057 | 0.66 | KDM4E (0.67) | KDM4EKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL8359975 | 0.66 | MAPT (0.52) | KDM4EKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL14960652 | 0.66 | KDM4E (0.46) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL29065895 | 0.66 | KDM4E (0.61) | KDM4EKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL21392852 | 0.65 | KDM4E (0.52) | KDM4EKMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL950298 | 0.65 | KDM4E (0.65) | KDM4EKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL30824582 | 0.65 | KDM4E (0.65) | KDM4EKMT2AMEN1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030651-A1 | GPX4 INHIBITORS AND USE THEREOF | SONATA THERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |