Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10051729 | 0.81 | CA1 (0.32) | CA1CA2 | |
| SCHEMBL14423719 | 0.77 | ALDH1A1 (0.33) | CA1CA2 | |
| SCHEMBL23706955 | 0.76 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL18665767 | 0.76 | EPHX1 (0.30) | — | |
| SCHEMBL10093713 | 0.76 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL14560943 | 0.74 | — | — | |
| SCHEMBL277765 | 0.73 | CA1 (0.43) | CA1CA2 | |
| SCHEMBL8526815 | 0.73 | CA1 (0.43) | CA1CA2 | |
| SCHEMBL12868893 | 0.73 | SLC1A3 (0.34) | — | |
| SCHEMBL12868885 | 0.73 | SLC1A3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030651-A1 | GPX4 INHIBITORS AND USE THEREOF | SONATA THERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |